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UID:0-6353@eng.ufl.edu
DTSTART;TZID=America/New_York:20240205T150000
DTEND;TZID=America/New_York:20240205T160000
DTSTAMP:20251201T182000Z
URL:https://www.eng.ufl.edu/news-events/events/bme-seminar-engineering-ins
 ights-into-type-1-diabetes/
SUMMARY:BME Seminar: Engineering Insights into Type 1 Diabetes
DESCRIPTION:Nikki Farnsworth\, Ph.D.\, Assistant Professor\, Chemical and B
 iological Engineering\, Colorado School of Mines\nBiosketch:\nDr. Nikki Fa
 rnsworth is an Assistant Professor of Chemical and Biological Engineering 
 at the Colorado School of Mines. She is also Affiliate Member and Adjunct 
 Assistant Professor at the Barbara Davis Center for Diabetes at the Anschu
 tz Medical Campus. Prior to joining the Mines faculty\, she completed her 
 postdoctoral training at the Barbara Davis Center for Diabetes in the Bioe
 ngineering and Pediatrics department under Dr. Richard Benninger\, working
  at the intersection of cell biology\, diabetes\, and biophysics. Dr. Farn
 sworth completed her Ph.D. and M.S. degrees in Chemical and Biological Eng
 ineering at the University of Colorado Boulder\, under Dr. Stephanie Bryan
 t working on cartilage tissue engineering. She completed her B.S. in Chemi
 cal Engineering at Rensselaer Polytechnic Institute. The Juvenile Diabetes
  Research Foundation\, the American Diabetes Association\, the NIH NIDDK\,
  the NIH Diabetes Research Center\, and the Helmsley Charitable Trust Geor
 ge Eisenbarth Award from nPOD currently fund her lab.\nAbstract:\nCurrentl
 y\, 1.25 million people in the United States have type 1 diabetes (T1D)\, 
 where the prevalence of T1D has increased by ~21% in the last decade. T1D 
 is characterized by the progressive destruction of the insulin producing 
 β-cells in the pancreatic islets of Langerhans. This leads to loss of blo
 od glucose homeostasis which can be deadly if left uncontrolled. The mecha
 nisms underlying disease onset and progression are not well understood\, l
 imiting the targets for potential therapeutics which could prevent the ons
 et or progression of T1D. The research goals of my lab are to utilize biom
 aterials as a tool to understand how disrupted islet function contributes 
 to T1D onset and progression and to develop targeted therapies to preserve
  islet function and survival in T1D. To achieve these goals\, my lab uses 
 a combination of engineering and biomolecular tools including advanced opt
 ical imaging techniques in live cells\, quantitative image analysis\, and 
 3D biomimetic hydrogel scaffolds. Our recent work has focused on developme
 nt a β-cell targeted drug delivery vehicle to deliver therapeutic cargo t
 o specifically to the islet β-cell. The results from our work will help t
 o improve targeted delivery of small peptides to the β-cell to prevent β
 -cell death in at risk individuals as well as preserve existing β-cells a
 nd promote islet graft survival in those with established T1D.
CATEGORIES:Seminars
LOCATION:Communicore Room C1-11\, 1249 Center Dr.\, Gainesville\, FL\, 3261
 0\, United States
GEO:29.640849;-82.34479
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