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BEGIN:VEVENT
UID:0-5797@eng.ufl.edu
DTSTART;TZID=America/New_York:20230417T150000
DTEND;TZID=America/New_York:20230417T160000
DTSTAMP:20230413T142914Z
URL:https://www.eng.ufl.edu/news-events/events/bme-seminar-in-vivo-imaging
 -of-neuroinflammation-in-patients-with-als-using-position-emission-tomogra
 phy/
SUMMARY:BME Seminar: In-vivo Imaging of Neuroinflammation in Patients with 
 ALS Using Position Emission Tomography
DESCRIPTION:Meena M. Makary\, Ph.D.\, Associate Professor at the Biomedical
  Engineering Department\, Cairo University\, and a Research Scientist at t
 he Athinoula A. Martinos Center\, Harvard Medical School\nNeuroinflammatio
 n is implicated in the pathophysiology of a growing number of human disord
 ers\, including multiple sclerosis\, chronic pain\, traumatic brain injury
 \, and amyotrophic lateral sclerosis (ALS). In this talk\, I will first pr
 esent the link between neuroinflammation and different clinical conditions
 \, and how it can be quantified in-vivo by tracking the distribution of th
 e translator protein (TSPO)\, which is dramatically upregulated by active 
 microglia and reactive astrocytes in pathological conditions. I will then 
 present a brief overview of the steps in PET imaging. Finally\, I will dis
 cuss our recent work on mapping the association of ALS presentation and pr
 ogression with neuroinflammatory signatures.\nDr. Makary is an Associate P
 rofessor at the Biomedical Engineering Department\, Cairo University\, and
  a Research Scientist at the Athinoula A. Martinos Center\, Harvard Medica
 l School. He received his B.Sc. and M.Sc. in Biomedical Engineering from C
 airo University\, Egypt in 2011 and 2013\, respectively. He received his P
 h.D. degree in Biomedical Engineering from Kyung Hee University\, South Ko
 rea in 2017. Dr. Makary completed his Postdoctoral Fellowship in the depar
 tment of Psychiatry at Yale University School of Medicine in 2019\, and th
 e departments of Psychiatry and Radiology at Harvard Medical School in 202
 2. In his M.Sc. work\, Dr. Makary’s research focused on developing signa
 l-processing algorithms and machine learning for Brain-Machine interfacing
  systems. In his doctoral work\, he used functional MRI (fMRI) to dissocia
 te the neural correlates of the specific and non-specific components of ac
 upuncture treatment in low back pain patients. He also developed a real-ti
 me fMRI neurofeedback paradigm that uses motor imagery to test its efficac
 y in treating motor deficits. At Yale University\, Dr. Makary used structu
 ral and functional imaging to study the brain signatures of chronic low-ba
 ck pain. He used Near-Infrared Spectroscopy to detect marijuana impairment
  at the Center of Addiction Medicine at the Massachusetts General Hospital
 . At Martinos Center\, Dr. Makary used simultaneous PET and MRI imaging to
  map the association of several neurodegenerative diseases' presentation a
 nd progression with neuroinflammatory signatures. Dr. Makary’s work has 
 been published in several major scientific journals such as Proceedings of
  National Academy of Science of the United States\, Neuron\, Brain &amp\; 
 Behavior and immunology\, Scientific Report\, and NeuroReport. His work ha
 s been cited by media outlets including The Boston Globe\, Scientific Amer
 ican\, Al-Ahram Egyptian Newspaper\, Cairo 24\, and EL-Massaa National mag
 azine.
CATEGORIES:Seminars
LOCATION:Communicore Room C1-17\, 1249 Center Dr.\, Gainesville\, FL\, 3261
 0\, United States
GEO:29.640849;-82.34479
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1249 Center Dr.\, Gainesvil
 le\, FL\, 32610\, United States;X-APPLE-RADIUS=100;X-TITLE=Communicore Roo
 m C1-17:geo:29.640849,-82.34479
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