1064 CENTER DR
Gainesville, Florida 32611
Healthcare Innovations &
Clean Energy: via Fluid Mechanics
Saikat Basu, Ph.D.
Postdoctoral Fellow at UNC Chapel Hill
Clinical therapeutics and clean energy are key topics of global importance, and fluid dynamics can play a critical role in both. Mechanistic understanding of flow-based drug transport in medical science is still nascent. Also, while the last few decades have witnessed a surge in renewable energy research, extracting energy from ubiquitous slow-moving streams is as yet an emergent area. I am leveraging my background in theoretical and computational fluid mechanics to synthesize a two-pronged interdisciplinary research program aimed at: (1) new understanding of clinical transport from an engineering perspective, (2) using vortex dynamics to develop new clean energy technologies. In the presentation, I will discuss the following:
Track 1. On the use of computational fluid dynamics (CFD) in investigating human respiratory functions and targeted drug uptake via breathed-in air.
Track 2. On reduced order modeling and classification of complex wake patterns comprising periodically shed vortices.
Under Track 1, I will further discuss my future research vision on the role of CFD to devise treatment recommendations for throat granulomas, on facilitating drug transmission to diseased nasal sinuses, and on delivery of drugs to the brain via nasal routes. The eventual goal is to establish CFD as a planning tool available to the doctors. Under Track 2, my next focus is on quantifying the vibrational response of a wake-shedding object, as a signature of the generated wake type. With some specific wake modes sharply enhancing the body oscillations, applications may include tapping the wake-induced motion to innovate new-age energy harvesters. Also, clinical flows frequently demonstrate vortices that can trap drug particulates, thereby obstructing their further transport. A deeper understanding of such interactions will require feedback from Track 2 to Track 1.
Dr. Saikat Basu is a Postdoctoral Fellow at the University of North Carolina at Chapel Hill. His projects at UNC-CH are on the use of computational and theoretical fluid mechanics to help improve medical therapeutics for nose and throat ailments. From 2014 – 2016, Dr. Basu was a Postdoctoral Scholar at the Okinawa Institute of Science and Technology, Japan. There he developed a mathematical model to predict the parameters for an impacting drop to bounce off a flowing soap film. The model also serves as a simple analogue for interfacial locomotion. In 2014, he completed his Ph.D. in Engineering Mechanics from Virginia Tech, under the supervision of Prof. Mark Stremler. Dr. Basu’s doctoral dissertation established an analytical framework to predict the downstream dynamics in some of the more complicated vortex wake arrangements, and was nominated for the outstanding dissertation award at the VT College of Engineering. Before this, he obtained his undergraduate B.E. degree in 2009 from Jadavpur University, India. Dr. Basu currently has an NIH R01 subcontract and is the PI on an ongoing pilot study funded by the NC Translational and Clinical Sciences Institute. His research has been covered by press on ScienceDaily, and on the international media outlets in Germany and in Italy.