BME Leadership Series: Dynamic Human Brain Imaging and Brain-Computer Interface

Date/Time

03/15/2021
3:00 pm-4:00 pm
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Leadership Seminar: Bin He, Ph.D., Trustee Professor and Head, Department of Biomedical Engineering, Carnegie Mellon University Dynamic Human Brain Imaging and Brain-Computer Interface

Brain activity is distributed over the 3-dimensional volume and evolves in time. Mapping spatio-temporal distribution of brain activation with high spatial resolution and high temporal resolution is of great importance for understanding the brain and aiding in the clinical diagnosis and management of brain disorders. Electrophysiological source imaging (ESI) from noninvasively recorded high density electroencephalogram (EEG) has played a significant role in advancing our ability to image brain function and dysfunction. We will discuss principles and current state of EEG-based ESI in localizing and imaging human brain activity with applications to imaging epileptic networks. Promising clinical results validated by intracranial recordings and surgical resection outcomes demonstrate the merits of noninvasive EEG-based ESI in mapping epileptogenic zones, aiding surgical treatment of intractable epilepsy. We will also discuss our recent progress in noninvasive brain-computer interface, for controlling of a robotic arm from noninvasive EEG signals using a motor imagery paradigm. Our work in a group of human subjects demonstrate the capability of controlling a virtual or physical device using only the “thoughts” as decoded from noninvasive recordings.

Biographical Sketch:

Bin He is Trustee Professor of Biomedical Engineering, Neuroscience, and by courtesy Electrical and Computer Engineering at Carnegie Mellon University. Dr. He has made significant research contributions to the fields of neuroengineering and biomedical imaging, including electrophysiological source imaging, brain-computer interface, and neuromodulation. His lab has demonstrated for the first time for humans to noninvasively control the flight of a drone and continuous move of a robotic arm using the “thought” alone. Dr. He has received a number of awards including the IEEE Biomedical Engineering Award, the William J. Molock Award, the Academic Career Achievement Award and the Distinguished Service Award from the IEEE Engineering in Medicine and Biology Society, among others. He served as a Past President of the IEEE Engineering in Medicine and Biology Society, and serves as the Chair of the International Academy of Medical and Biological Engineering. Dr. He also served as Editor-in-Chief of IEEE Transactions on Biomedical Engineering from 2013-2018, and as Member of NIH BRAIN Initiative Multi-Council Working Group from 2014-2019. He is an elected Fellow of International Academy of Medical and Biological Engineering, IEEE, American Institute of Medical and Biological Engineering, and Biomedical Engineering Society.

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